CAID

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Service models

Gout

C57BL/6 mice are economical, healthy and highly sensitive to gout-inducing monosodium urate, and using this model, we provide preclinical efficacy evaluation services for gout treatment drugs.

보유모델 정보
Model Evaluation interval Evaluation items
C57BL/6
(peritonitis model)
(airpouch model)
Same day
7th day after air injection
  • Whole cell count, / neutrophil count within lavage fluid, IL-1ß of inflammatory cytokine
  • Tissue block of back skin and analysis of inflammatory cell infiltration (airpouch model)

Peritonitis model

  • Whole cell count in peritoneal lavage fluid using automated cell counter (ADAMTM)
  • Cytometry using neutrophil-specific marker and neutrophil count
  • Quantitative analysis of IL-1ß in lavage fluid

Airpouch model

  • Whole cell count in pouch lavage fluid using automated cell counter (ADAMTM)
  • Cytometry using neutrophil-specific marker and neutrophil count
  • Quantitative analysis of IL-1ß in lavage fluid
  • Inflammation analysis of back skin (H&E stain)
  • Chemical stain of IL-1ß immune tissue in back skin*
  • Other customized analysis*
* Premium Service